GINECOLOGIA DE NOVAK BY BROS PDF

Kasida The laboratory is a private practice, serving a low-risk population in Mexico City, Mexico. In this study, we analyzed samples obtained with or without cleaning the cervix, and compared their contents in order to determine the sensitivity and specificity of these two methods. Accordingly, the authors concluded that the cervix should be wiped at the discretion of ginecoloyia clinician. Principles and practice of colposcopy.

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Fenrilkree In this study, we analyzed samples obtained with or without cleaning the cervix, and compared their contents in order to determine the sensitivity and specificity of these two methods.

Cervical cleaning improves Pap smear quality. The laboratory is ny private practice, serving a low-risk population in Mexico City, Tinecologia. If not cleaned, the mucus may prevent the instrument from obtaining cells from the cervical surface. False positive frequency in CS samples.

Of patients who underwent cytology and colposcopy, Koss [ 19 ] answers this question by referring to some very early papers, including Sedlis ginecokogia al. Thus, gently removing the CS without touching the cervical surface should be recommended in any procedure for obtaining a cervical cytology sample. A Resource Pack for Trainers. The sensitivity and specificity were calculated using biopsy as the gold standard. J Low Gen Tract Dis. Of the cases, ASs were found in Accordingly, the authors concluded that the cervix should be wiped at the discretion of the clinician.

Conversely, the CS was in contact with the vaginal wall and contained diagnostic cells in this case, and the biopsy found a typical condyloma with koilocytes.

The reference standard for the positive true diagnosis was the combined results of the biopsy and p16 staining, whereas a true negative diagnosis was based on negative results for CIN in the biopsy [ 16 ] and negative p16 staining [ ]. All patients referred to the laboratory for a second opinion had previous CIN detected 1 to 6 months earlier. Sample characteristic and kind of inflammation detected in the histophatologycal analyze in CS and Gincologia respectively.

Cervical sampling including CS results in lower sensitivity and CIN detection rates, and in more inflammatory reactions. Open in a separate window. The samples should be obtained by trained personnel, including gynecologists, and ideally, the sample should be taken from the transformation zone TZ [ 23 ]. Based on our results herein, we believe that cervical samples containing CS are not optimal, as the rate of ASs is low.

The SS resulted novxk a higher proportion of adequate samples being obtained Does liquid-based technology novka improve detection of cervical neoplasia? The results are expressed in percentages and frequencies for all parameters.

Please review our privacy policy. Abstract Sensitivity of cervical cytology is suboptimal, ginefologia in developing countries such as Mexico, despite available guidelines aimed at improving this. In cytology cases of atypical squamous cells of undetermined significance ASC-US or in which a high-grade squamous intraepithelial lesion could not be excluded ASC-Hadditional slides were analyzed for p16 expression to confirm or rule out CIN.

All patients provided informed consent, and an external ethical committee approved the study protocol. CS was removed and compared with the clean, second sample SS using in both liquid-based cytology.

One positive case detected in the CS was not detected in the SS. All biopsy samples were stained with hematoxylin and eosin as per standard protocol and analyzed by immunohistochemical staining for cyclin-dependent kinase inhibitor 2A p16 clone J6; Cell Marke, CA, USAusing the CIN classification [ 16 ].

CS is the result of exfoliated cells from the cervix and vaginal wall, and contains inflammatory cells and bacteria dee addition to the mucus secreted from the endocervical glands, which are normally found in the cervical orifice. The false negative rate was lower in the SS Ginecoolgia 4. In this study, we compared the CS removed without touching the cervical surface to the SS to evaluate the adequacy of both samples, and to obtain and compare their sensitivity, specificity, and positive and negative predictive values.

The SS was obtained from the transformation zone using a cervical cytobrush or broom depending of the nature of the TZ.

Schematic of the procedure for removing cervical mucus. By excluding CS from cervical samples, the sensitivity could be improved and the false negative rate could be reduced.

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In our study, the only positive case detected in the CS not detected in the SS was a lesion in the vaginal wall that was not accessible to the instrument for sampling the cervix in the SS. One positive case detected in the CS was not detected in the SS. The methods for obtaining samples have been described elsewhere [ 4 — 8 ]. The inflammatory reaction was moderate-to-severe in In B the atypia is more clearly defined, less inflammatory cells on SS. If not cleaned, the mucus may prevent the instrument from obtaining cells from the cervical surface. Sample characteristic and kind of inflammation detected in the histophatologycal analyze in CS and SS respectively.

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GINECOLOGIA DE NOVAK BY BROS PDF

Fenrilkree In this study, we analyzed samples obtained with or without cleaning the cervix, and compared their contents in order to determine the sensitivity and specificity of these two methods. Cervical cleaning improves Pap smear quality. The laboratory is ny private practice, serving a low-risk population in Mexico City, Tinecologia. If not cleaned, the mucus may prevent the instrument from obtaining cells from the cervical surface. False positive frequency in CS samples.

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