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Unitermos Abstract Erythropoietin EPO is a hormone with a very significant activity for the erythroid organic function, responsible for stimulating the production of erythrocytes. Initially the EPO has been used in medicine as an option for treating disorders such as anemia consequent to renal failure or alternative for patients who require frequent blood transfusions. However, the synthetic form of this hormone is also being used for illegal purposes: doping in sports as part of elite competitive athletes.

Erythropoietin provides benefits on oxygenation, as well as it is responsible for the increase in pharmacokinetics potentiality of hemoglobin, leading to a more effective aerobic power, which generates an increase in sports capacity of endurance athletes.

However, concomitant to the benefits, some athletes may experience the adverse effects caused by the indiscriminate use of synthetic erythropoietin, which has become a serious problem in the sports scope. Allied to this, there is a laboratory detection that still has shortcomings and needs improvement, since the different isoforms of synthetic EPO have similar characteristics.

Keywords : Erythropoietin. Recombinant Human Erythropoietin. Sua estrutura pode ser visualizada na figura 1. Figura 1.

Figura 2. Figura 3. Estes dados podem ser observados na tabela Tabela 1. Dados fornecidos pela WADA referentes aos resultados de testes anti-doping realizados no ano de 31 Tabela 2. Dados fornecidos pela WADA referentes aos resultados de testes anti-doping realizados no ano de 31 Tabela 3. Dados fornecidos pela WADA referentes aos resultados de testes anti-doping realizados no ano de 31 Tabela 4.

Dados fornecidos pela WADA referentes aos resultados de testes anti-doping realizados no ano de 31 Tabela 5. Bento, R. Erythropoietin: physico and biochemical analysis. J Chromatogr B ; Adamson JW. Regulation of red blood cell production. Am J Med ;S Erythropoietin abuse in athletes.

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