LIPEMIA RETINALIS PDF

Combined hyperlipidaemia may occur as a primary familial or secondary acquired abnormality. In this report we describe a 3 month old baby with lipaemia retinalis. At presentation there was creamy white appearance of retinal blood vessels with no extravasation of lipid or blood. Triglycerides and cholesterol were raised at presentation. Following low fat diet and treatment serum triglyceride and cholesterol levels decreased significantly with complete resolution of fundus changes. Keywords :hyperlipoproteinaemia, hypertriglyceridaemia, cholesterol, lipaemia retinalis Introduction Lipaemia retinalis is a rare condition which can occur in both primary and secondary hyperlipidemias, It was first described in by Heyl.

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Received Jun 4; Accepted Nov This article has been cited by other articles in PMC. Summary Background Hyperlipidemia is an identified factor of premature vessel atherosclerosis. Lipemia retinalis is an unusual retinal manifestation of hyperlipidemia and is thought to be directly correlated with the serum triglyceride level. Case Report This paper discusses the case of a year-old patient with lipemia retinalis, which deteriorated his visual acuity.

The normalization of serum lipids, reversion of retinal vessels alterations and visual acuity improvement was achieved after an intensive statin lipid-lowering therapy. Conclusions Hyperlipidemia can cause lipemia retinalis, which is characterized by the hyperlipidemic vascular lesions-whitish color of vessels, lipid infiltration into the retina and decrease of visual acuity.

The lipid-lowering therapy may lead to the normalization of the appearance of the fundus and restore the visual acuity. The consequences of hyperlipidemia are multiorgan and include premature atherosclerosis with all its effects, lesions of the digestive system liver and pancreas , skin and sometimes ocular changes [ 1 ]. Lipemia retinalis is a rare retinal manifestation of hypertriglyceridemia [ 2 — 4 ].

It was first described by Heyl in [ 5 ]. Retinal vessels become cream colored due to the scattering of light by the triglyceride-laden chylomicrons. Very high levels of triglycerides are required; hypercholesterolemia alone does not produce this vascular appearance [ 2 ].

In clinical practice, elevated serum triglycerides are most often observed in persons with metabolic syndrome, despite the fact that secondary or genetic factors can heighten triglyceride levels [ 6 ]. Case Report We report the case of a year-old patient treated for age-related macular degeneration who had exudative form in the right eye and non-exudative in the left eye for 2 years, and presented a deterioration of vision in his left eye.

For this reason, preparations containing antioxidants, vitamins and minerals Zinc were prescribed. However, it is not certain that he used them systematically. He had also a history of lipid disorder high serum cholesterol and dyslipidemia in anamnesis. The visual acuity in his right eye was counting fingers at 2 m and acuity in his left eye decreased from 0. Eye fundus examination revealed lipemia retinalis; the hyperlipidemic vascular lesions had whitish-colored vessels and lipid infiltration into the retina and age-related macular degeneration in both eyes.

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Lipemia Retinalis

You can help by adding to it. October This section may contain excessive or inappropriate references to self-published sources. Please help improve it by removing references to unreliable sources where they are used inappropriately. October Learn how and when to remove this template message Fundus photograph showing the blood vessels in a normal human retina. Veins are darker and slightly wider than corresponding arteries.

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Lipemia retinalis - an unusual cause of visual acuity deterioration.

Multiple genes responsible for triglyceride metabolism have been identified as causing the serum triglyceride levels to see characteristic retinal vasculature abnormalities. Individuals with severe hypertriglyceridemia tended to be men However, genotype—phenotype correlations have not been established, as there is no established association between the nature or location of the mutation, age at diagnosis, lipid levels, and severity of symptoms. It serves as a vital clinical sign of hypertriglyceridemia because acute triglyceride elevations may be asymptomatic at first, delaying treatment of a potentially lethal metabolic disorder as elevations of this magnitude may lead to cardiovascular consequences including heart attack or stroke. The clinical appearance is graded accordingly as early, moderate, or marked Stages I-III, respectively. Primary prevention Reduction and control of serum triglyceride levels will prevent lipemia retinalis from developing. Correction of the lipid levels may reverse the abnormal findings within one week.

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